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Managing stakeholder dynamics and complexity in mega infrastructure projects

Geoffrey Qiping SHEN, Jin XUE

《工程管理前沿（英文）》 2021年 第8卷 第1期   页码 148-150 doi: 10.1007/s42524-020-0149-6

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Decreasing complexity of glucose time series derived from continuous glucose monitoring is correlated

《医学前沿（英文）》 2023年 第17卷 第1期   页码 68-74 doi: 10.1007/s11684-022-0955-9

摘要： Most information used to evaluate diabetic statuses is collected at a special time-point, such as taking fasting plasma glucose test and providing a limited view of individual’s health and disease risk. As a new parameter for continuously evaluating personal clinical statuses, the newly developed technique “continuous glucose monitoring” (CGM) can characterize glucose dynamics. By calculating the complexity of glucose time series index (CGI) with refined composite multi-scale entropy analysis of the CGM data, the study showed for the first time that the complexity of glucose time series in subjects decreased gradually from normal glucose tolerance to impaired glucose regulation and then to type 2 diabetes (P for trend < 0.01). Furthermore, CGI was significantly associated with various parameters such as insulin sensitivity/secretion (all P < 0.01), and multiple linear stepwise regression showed that the disposition index, which reflects β-cell function after adjusting for insulin sensitivity, was the only independent factor correlated with CGI (P < 0.01). Our findings indicate that the CGI derived from the CGM data may serve as a novel marker to evaluate glucose homeostasis.

关键词： complexity of glucose time series     continuous glucose monitoring     impaired glucose regulation     insulin secretion and sensitivity     refined composite multi-scale entropy    

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Applications of dynamical complexity theory in traditional Chinese medicine

null

《医学前沿（英文）》 2014年 第8卷 第3期   页码 279-284 doi: 10.1007/s11684-014-0367-6

摘要：

Traditional Chinese medicine (TCM) has been gradually accepted by the world. Despite its widespread use in clinical settings, a major challenge in TCM is to study it scientifically. This difficulty arises from the fact that TCM views human body as a complex dynamical system, and focuses on the balance of the human body, both internally and with its external environment. As a result, conventional tools that are based on reductionist approach are not adequate. Methods that can quantify the dynamics of complex integrative systems may bring new insights and utilities about the clinical practice and evaluation of efficacy of TCM. The dynamical complexity theory recently proposed and its computational algorithm, Multiscale Entropy (MSE) analysis, are consistent with TCM concepts. This new system level analysis has been successfully applied to many health and disease related topics in medicine. We believe that there could be many promising applications of this dynamical complexity concept in TCM. In this article, we propose some promising applications and research areas that TCM practitioners and researchers can pursue.

关键词： traditional Chinese medicine     Multiscale Entropy     dynamical complexity     system level     applications    

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Managing Coordination Complexity in the Remanufacturing of Aircraft Engines

Qing Yang,Lu Zheng

《工程管理前沿（英文）》 2016年 第3卷 第2期   页码 158-164 doi: 10.15302/J-FEM-2016022

摘要： The complexity of communication and coordination stemming from teams responsible for adjusting interdependent parameters of components is a fundamental feature in the aircraft engine remanufacturing engineering project. To manage coordination complexity, the features of the remanufacturing process of aircraft engine are analyzed and a systematic method is presented to measure and optimize the dependency between coupled components. Furthermore, quantitative models are built based on Design Structure Matrix (DSM) models to measure dependency strengths related to the parameter features of the components. Also, a two-stage DSM clustering criteria is used to reduce the complexity of an organization. An industrial example is provided to illustrate the proposed models. The results showed that the proposed approach can reduce total coordination complexity.

关键词： remanufacturing engineering project     aircraft engine     coordination complexity     organization optimization     design structure matrix (DSM)    

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试析战略创新的复杂性

苗东升

《中国工程科学》 2007年 第9卷 第1期   页码 8-14

摘要：

指明了战略创新研究属于复杂性科学，依据系统学原理诠释创新概念；论述了战略创新的复杂性在 于它自身内含的对立统一；论证了国家战略创新是开放复杂巨系统，并指出驾驭这种复杂性需要建设创新型 国家。

关键词： 战略创新     复杂性     系统思维     创新型国家    

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Traditional Chinese medicine: potential approaches from modern dynamical complexity theories

null

《医学前沿（英文）》 2016年 第10卷 第1期   页码 28-32 doi: 10.1007/s11684-016-0434-2

摘要：

Despite the widespread use of traditional Chinese medicine (TCM) in clinical settings, proving its effectiveness via scientific trials is still a challenge. TCM views the human body as a complex dynamical system, and focuses on the balance of the human body, both internally and with its external environment. Such fundamental concepts require investigations using system-level quantification approaches, which are beyond conventional reductionism. Only methods that quantify dynamical complexity can bring new insights into the evaluation of TCM. In a previous article, we briefly introduced the potential value of Multiscale Entropy (MSE) analysis in TCM. This article aims to explain the existing challenges in TCM quantification, to introduce the consistency of dynamical complexity theories and TCM theories, and to inspire future system-level research on health and disease.

关键词： traditional Chinese medicine     quantification     dynamical complexity     system level     balance     modern sciences    

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From systematicness to complexity: Fundamental thinking of mega-project management

Zhaohan SHENG, Han LIN

《工程管理前沿（英文）》 2018年 第5卷 第1期   页码 125-127 doi: 10.15302/J-FEM-2018001

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How does the improved DB mode degrade the complex integrity of infrastructure mega-projects? Evidence from the Hong Kong-Zhuhai-Macao Bridge project in China

Jinwen ZHANG, Yumin QIU

《工程管理前沿（英文）》 2018年 第5卷 第1期   页码 40-51 doi: 10.15302/J-FEM-2018083

摘要： Complex integrity is one of the main characteristics of infrastructure mega-projects (IMPs). Cost, technology, risk, duration, environmental impact, and other uncertain complexities are interrelated and constitute a challenging and complex management problem. At present, there is no unified understanding of or solutions to these complex integrity problems. This study analyzes the complex integrity of the island-tunnel subproject of the Hong Kong-Zhuhai-Macao Bridge (HZMB) project and proposes an improved design-build (DB) mode in which the owner provides a preliminary design and has the right to form and manage consortium. This improved DB mode creatively degrades the special complexities that arise from multiple dimensions. On this basis, it is an efficacious way to grasp the main contradictions, integrate the effective resources, and degrade the complex integrity in multiple dimensions and at multiple levels so as to effectively deal with the complexity management of IMPs.

关键词： Hong Kong-Zhuhai-Macao Bridge project     island-tunnel subproject     complex integrity     complexity degradation     the general contracting mode of design-build     the design-build consortium    

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Epithelial-to-mesenchymal transition in cancer: complexity and opportunities

Yun Zhang, Robert A. Weinberg

《医学前沿（英文）》 2018年 第12卷 第4期   页码 361-373 doi: 10.1007/s11684-018-0656-6

摘要：

The cell-biological program termed the epithelial-to-mesenchymal transition (EMT) plays an important role in both development and cancer progression. Depending on the contextual signals and intracellular gene circuits of a particular cell, this program can drive fully epithelial cells to enter into a series of phenotypic states arrayed along the epithelial-mesenchymal phenotypic axis. These cell states display distinctive cellular characteristics, including stemness, invasiveness, drug-resistance and the ability to form metastases at distant organs, and thereby contribute to cancer metastasis and relapse. Currently we still lack a coherent overview of the molecular and biochemical mechanisms inducing cells to enter various states along the epithelial-mesenchymal phenotypic spectrum. An improved understanding of the dynamic and plastic nature of the EMT program has the potential to yield novel therapies targeting this cellular program that may aid in the management of high-grade malignancies.

关键词： epithelial-to-mesenchymal transition     cancer     metastasis     cancer stem cell    

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An improved low-complexity sum-product decoding algorithm for low-density parity-check codes

Michaelraj Kingston ROBERTS,Ramesh JAYABALAN

《信息与电子工程前沿（英文）》 2015年 第16卷 第6期   页码 511-518 doi: 10.1631/FITEE.1400269

摘要： In this paper, an improved low-complexity sum-product decoding algorithm is presented for low-density parity-check (LDPC) codes. In the proposed algorithm, reduction in computational complexity is achieved by utilizing fast Fourier transform (FFT) with time shift in the check node process. The improvement in the decoding performance is achieved by utilizing an optimized integer constant in the variable node process. Simulation results show that the proposed algorithm achieves an overall coding gain improvement ranging from 0.04 to 0.46 dB. Moreover, when compared with the sum-product algorithm (SPA), the proposed decoding algorithm can achieve a reduction of 42%-67% of the total number of arithmetic operations required for the decoding process.

关键词： Computational complexity     Coding gain     Fast Fourier transform (FFT)     Low-density parity-check (LDPC) codes     Sum-product algorithm (SPA)    

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Grasping institutional complexity in infrastructure mega-projects through the multi-level governance

Yi HU, Yun LE, Xinglin GAO, Yongkui LI, Mingqiang LIU

《工程管理前沿（英文）》 2018年 第5卷 第1期   页码 52-63 doi: 10.15302/J-FEM-2018074

摘要： This study analyzes the design and operation of multi-level governance system for the smooth delivery of infrastructure mega-projects with high institutional complexity caused by market transition. From an institutional perspective, this study scrutinizes the structure, elements, and dynamics of the governance system of infrastructure mega-projects and then proposes an integrative framework based on the inductive case study of the Hong Kong-Zhuhai-Macao Bridge mega-project. Multiple evidences of archives, field studies, and interviews related to the case project are triangulated to further analyze the institutional effects, specifically those with government logics and market structures, on the design and operation of the three-level governance system. Results reveal that the co-evolution between governments and markets in China has shaped the vertical levels of the mega-project governance system and has further affected their evolution and operation across various stages of project development. This study contributes to the rapidly emerging research on complex system governance by proposing a systematic model of three-level mega-project governance to enhance the timely delivery of infrastructure mega-projects within budget.

关键词： institutional complexity     multi-level governance     infrastructure mega-project     China    

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从复杂性看科学发展观

苗东升

《中国工程科学》 2005年 第7卷 第8期   页码 1-8

摘要：

发展观指人们对社会发展的目标、动力、模式、规律等的根本看法，其复杂性涉及四个层面：在对象层面上，发展观的复杂性源于社会是特殊的开放复杂巨系统；在认知层面上，认知过程的复杂性源于思维巨系统的复杂性与习以为常的还原论和非系统思维带来的曲解；在实践层面上，落实发展观的复杂性源于现实的利益格局、现行体制中的不完善、国际关系的复杂性等因素；在哲学层面上，发展观的复杂性源于发展过程包含的大量对立统一，只有对它们统筹兼顾，确保矛盾各方全面协调发展，才是科学的。

关键词： 科学发展观     复杂性     开放复杂巨系统     对立统一    

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Influence of construction-induced damage on the degradation of freeze–thawed lightweight cellular concrete

《结构与土木工程前沿（英文）》 2021年 第15卷 第3期   页码 781-792 doi: 10.1007/s11709-021-0733-9

摘要： During the construction of lightweight cellular concrete (LCC), material damage frequently occurs, causing the degradation and deterioration of the mechanical performance, durability, and subgrade quality of LCC. The construction-induced damage can be more significant than those from the service environment of LCC, such as freeze–thaw (F–T) action in cold regions. However, the effect of construction-induced damage on LCC during F–T cycles is often ignored and the deterioration mechanisms are not yet clarified. In this study, we investigated the factors causing damage during construction using a sample preparation method established to simulate the damage in the laboratory setting. We conducted F–T cycle tests and microstructural characterization to study the effect of microstructural damage on the overall strength of LCC with different water contents under F–T actions. We established the relationship between the pore-area ratio and F–T cycle times, pore-area ratio, and strength, as well as the F–T cycle times and strength under different damage forms. The damage evolution is provided with the rationality of the damage equation, verified by comparing the measured and predicted damage variables. This study would serve as a guide for the construction and performance of LCC in cold regions.

关键词： lightweight cellular concrete     construction-induced damage     freeze-thaw action     microstructure     degradation mechanism    

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Efficient degradation of orange II by ZnMn

Qingzhuo Ni, Hao Cheng, Jianfeng Ma, Yong Kong, Sridhar Komarneni

《化学科学与工程前沿（英文）》 2020年 第14卷 第6期   页码 956-966 doi: 10.1007/s11705-019-1907-z

摘要： A ZnMn O catalyst has been synthesized via a sucrose-aided combustion method and characterized by various analytical techniques. It is composed of numerous nanoparticles (15–110 nm) assembled into a porous structure with a specific surface area (SSA) of 19.1 m ·g . Its catalytic activity has been investigated for the degradation of orange II dye using three different systems, i.e., the photocatalysis system with visible light, the chemocatalysis system with bisulfite, and the photo-chemical catalysis system with both visible light and bisulfite. The last system exhibits the maximum degradation efficiency of 90%, much higher than the photocatalysis system (15%) and the chemocatalysis system (67%). The recycling experiments indicate that the ZnMn O catalyst has high stability and reusability and is thus a green and eximious catalyst. Furthermore, the potential degradation mechanisms applicable to the three systems are discussed with relevant theoretical analysis and scavenging experiments for radicals. The active species such as Mn(III), O , h , e , SO and HO are proposed to be responsible for the excellent degradation results in the photo-chemical catalysis system with the ZnMn O catalyst.

关键词： ZnMn2O4     photo-chemical catalysis     bisulfite     dye degradation    

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Promotive effect of pyridine on indole degradation by activated sludge under anoxic conditions

LI Yongmei, GU Guowei, LI Wenshu

《环境科学与工程前沿（英文）》 2007年 第1卷 第4期   页码 493-497 doi: 10.1007/s11783-007-0079-0

摘要： Batch experiments were carried out to investigate the promotive effect of pyridine on indole degradation under denitrifying conditions. The seed sludge was obtained from a local coal-coking wastewater treatment facility and was acc

关键词： wastewater treatment     coal-coking wastewater     promotive     degradation    

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标题 作者 时间 类型 操作

Managing stakeholder dynamics and complexity in mega infrastructure projects

Geoffrey Qiping SHEN, Jin XUE

期刊论文

Decreasing complexity of glucose time series derived from continuous glucose monitoring is correlated

期刊论文

Applications of dynamical complexity theory in traditional Chinese medicine

null

期刊论文

Managing Coordination Complexity in the Remanufacturing of Aircraft Engines

Qing Yang,Lu Zheng

期刊论文

试析战略创新的复杂性

苗东升

期刊论文

Traditional Chinese medicine: potential approaches from modern dynamical complexity theories

null

期刊论文

From systematicness to complexity: Fundamental thinking of mega-project management

Zhaohan SHENG, Han LIN

期刊论文

How does the improved DB mode degrade the complex integrity of infrastructure mega-projects? Evidence from the Hong Kong-Zhuhai-Macao Bridge project in China

Jinwen ZHANG, Yumin QIU

期刊论文

Epithelial-to-mesenchymal transition in cancer: complexity and opportunities

Yun Zhang, Robert A. Weinberg

期刊论文

An improved low-complexity sum-product decoding algorithm for low-density parity-check codes

Michaelraj Kingston ROBERTS,Ramesh JAYABALAN

期刊论文

Grasping institutional complexity in infrastructure mega-projects through the multi-level governance

Yi HU, Yun LE, Xinglin GAO, Yongkui LI, Mingqiang LIU

期刊论文

从复杂性看科学发展观

苗东升

期刊论文

Influence of construction-induced damage on the degradation of freeze–thawed lightweight cellular concrete

期刊论文

Efficient degradation of orange II by ZnMn

Qingzhuo Ni, Hao Cheng, Jianfeng Ma, Yong Kong, Sridhar Komarneni

期刊论文

Promotive effect of pyridine on indole degradation by activated sludge under anoxic conditions

LI Yongmei, GU Guowei, LI Wenshu

期刊论文